Cardiovascular

📑 Journal Club Articles

Newborn Screening for Critical Congenital Heart Disease: A New Algorithm and Other Updated Recommendations: Clinical Report.

Oster ME, Pinto NM, Pramanik AK, Markowsky A, Schwartz BN, Kemper AR, Hom LA, Martin GR; and the SECTION ON CARDIOLOGY AND CARDIAC SURGERY; SECTION ON HOSPITAL MEDICINE; COMMITTEE ON FETUS AND NEWBORN.Pediatrics. 2025 Jan 1;155(1):e2024069667. doi: 10.1542/peds.2024-069667.PMID: 39679594

Changes in Patent Ductus Arteriosus Management and Outcomes in Infants Born at 26 to 28 Weeks' Gestation.

Kaluarachchi DC, Rysavy MA, Do B, Chock VY, Laughon MM, Backes CH, Colaizy TT, Bell EF, McNamara PJ.J Pediatr. 2024 Dec 26:114456. doi: 10.1016/j.jpeds.2024.114456. Online ahead of print.PMID: 39732160

Hemodynamic assessment by neonatologist using echocardiography: Primary provider versus consultation model.

Noori S, Ramanathan R, Lakshminrusimha S, Singh Y. Pediatr Res. 2024 May 22. doi: 10.1038/s41390-024-03248-7. Online ahead of print. PMID: 38778230

Impact of targeted neonatal echocardiography consultations for critically sick preterm neonates.

Joye S, Kharrat A, Zhu F, Deshpande P, Baczynski M, Jasani B, Lee S, Mertens LL, McNamara PJ, Shah PS, Weisz DE, Jain A.Arch Dis Child Fetal Neonatal Ed. 2024 Sep 3:fetalneonatal-2024-327347. doi: 10.1136/archdischild-2024-327347. Online ahead of print.PMID: 39227145

Transcatheter and Surgical Ductus Arteriosus Closure in Very Low Birth Weight Infants: 2018-2022.

Leahy BF, Edwards EM, Ehret DEY, Soll RF, Yeager SB, Flyer JN. Pediatrics. 2024 Aug 1;154(2):e2024065905. doi: 10.1542/peds.2024-065905.PMID: 39005106

Impact of targeted neonatal echocardiography consultations for critically sick preterm neonates.

Oral sildenafil versus bosentan for treatment of persistent pulmonary hypertension of the newborn: a randomized controlled trial.

Kallimath A, Deshpande S, Singh P, Garegrat R, Lakshminrusimha S, Maheshwari R, Suryawanshi P.BMC Pediatr. 2024 Nov 1;24(1):698. doi: 10.1186/s12887-024-05107-0.PMID: 39487423 Free PMC article. Clinical Trial.

Vasopressin as adjunctive therapy in pulmonary hypertension associated with refractory systemic hypotension in term newborns.

Santelices F, Masoli D, Kattan J, Toso A, Luco M.J Perinatol. 2024 Jul 4. doi: 10.1038/s41372-024-02015-0. Online ahead of print.PMID: 38965377

Long term follow-up of patients with patent ductus arteriosus after transcatheter closure.

Peng Y, Cheng Z, Zhang Y, Yi Q.Pediatr Res. 2024 Jun 14. doi: 10.1038/s41390-024-03317-x. Online ahead of print.PMID: 38877281

Retrospective study of preterm infants exposed to inhaled nitric oxide in Kaiser Permanente Southern California: morbidity, mortality and follow-up.

Bhatt DR, Braun D, Dizon RA, Shi JM, Weerasinghe S, Sabio A, Reddy S, Lee HC, Ramanathan R, Lakshminrusimha S.J Perinatol. 2024 Jul 18. doi: 10.1038/s41372-024-02051-w. Online ahead of print.PMID: 39025953

Transcatheter and Surgical Ductus Arteriosus Closure in Very Low Birth Weight Infants: 2018-2022.

Leahy BF, Edwards EM, Ehret DEY, Soll RF, Yeager SB, Flyer JN.Pediatrics. 2024 Jul 15:e2024065905. doi: 10.1542/peds.2024-065905. Online ahead of print.PMID: 39005106

Procedural closure of the patent ductus arteriosus in preterm infants: a clinical practice guideline.

Mitra S, Bischoff AR, Sathanandam S, Lakshminrusimha S, McNamara PJ.J Perinatol. 2024 Jul 12. doi: 10.1038/s41372-024-02052-9. Online ahead of print.PMID: 38997403 Review.

Acetaminophen for Patent Ductus Arteriosus and Risk of Mortality and Pulmonary Morbidity.

Jensen EA, DeMauro SB, Rysavy MA, Patel RM, Laughon MM, Eichenwald EC, Do BT, Das A, Wright CJ; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.Pediatrics. 2024 Jul 16:e2023065056. doi: 10.1542/peds.2023-065056. Online ahead of print.PMID: 39011550

Perioperative Brain Injury in Relation to Early Neurodevelopment Among Children with Severe Congenital Heart Disease: Results from a European Collaboration.

Neukomm A, Claessens NHP, Bonthrone AF, Stegeman R, Feldmann M, Nijman M, Jansen NJG, Nijman J, Groenendaal F, de Vries LS, Benders MJNL, Breur JMPJ, Haas F, Bekker MN, Logeswaran T, Reich B, Kottke R, Dave H, Simpson J, Pushparajah K, Kelly CJ, Arulkumaran S, Rutherford MA, Counsell SJ, Chew A, Knirsch W, Sprong MCA, van Schooneveld MM, Hagmann C, Latal B; European Association Brain in Congenital Heart Disease (EU-ABC) consortium.

J Pediatr. 2024 Mar;266:113838. doi: 10.1016/j.jpeds.2023.113838. Epub 2023 Nov 22.

PMID: 37995930 Free article.

Placental Pathology Contributes to Impaired Volumetric Brain Development in Neonates With Congenital Heart Disease.

Nijman M, van der Meeren LE, Nikkels PGJ, Stegeman R, Breur JMPJ, Jansen NJG, Ter Heide H, Steenhuis TJ, de Heus R, Bekker MN, Claessens NHP, Benders MJNL; CHD LifeSpan Study Group ‡.

J Am Heart Assoc. 2024 Mar 5;13(5):e033189. doi: 10.1161/JAHA.123.033189. Epub 2024 Feb 29.

PMID: 38420785 Free PMC article.

Response categorization and outcomes in extremely premature infants born at 22-26 weeks gestation that received inhaled nitric oxide for hypoxic respiratory failure.

Boly TJ, Dagle JM, Klein JM, Rios DR, McNamara PJ, Giesinger RE.

J Perinatol. 2023 Mar;43(3):324-331. doi: 10.1038/s41372-022-01582-4. Epub 2022 Dec 12.

PMID: 36509816 Free PMC article.

Patent Ductus Arteriosus and Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension: A Bayesian Meta-Analysis.

Villamor E, van Westering-Kroon E, Gonzalez-Luis GE, Bartoš F, Abman SH, Huizing MJ.

JAMA Netw Open. 2023 Nov 1;6(11):e2345299. doi: 10.1001/jamanetworkopen.2023.45299.

PMID: 38015504 Free PMC article.

Cardiopulmonary physiological effects of diuretic therapy in preterm infants with chronic pulmonary hypertension.

Zhu F, Ibarra Rios D, Joye S, Baczynski M, Rios D, Giesinger RE, McNamara PJ, Jain A.

J Perinatol. 2023 Oct;43(10):1288-1294. doi: 10.1038/s41372-023-01742-0. Epub 2023 Aug 7.

PMID: 37550529

Vasopressin in newborns with refractory acute pulmonary hypertension.

Ouellet S, Drolet C, Morissette G, Pellerin A, Hébert A.Pediatr Res. 2024 May;95(6):1572-1577. doi: 10.1038/s41390-023-02995-3. Epub 2024 Jan 11.PMID: 38212386

Impact of early screening echocardiography and targeted PDA treatment on neonatal outcomes in "22-23" week and "24-26" infants.

Giesinger RE, Hobson AA, Bischoff AR, Klein JM, McNamara PJ.

Semin Perinatol. 2023 Mar;47(2):151721. doi: 10.1016/j.semperi.2023.151721. Epub 2023 Mar 5.

PMID: 36882362

EBNEO commentary: Patent ductus arteriosus (PDA)-To treat early or not with ibuprofen?

Javed R, Gowda H.Acta Paediatr. 2024 Apr 30. doi: 10.1111/apa.17259. Online ahead of print.PMID: 38687140 No abstract available.

Trial of Selective Early Treatment of Patent Ductus Arteriosus with Ibuprofen.

Gupta S, Subhedar NV, Bell JL, Field D, Bowler U, Hutchison E, Johnson S, Kelsall W, Pepperell J, Roberts T, Sinha S, Stanbury K, Wyllie J, Hardy P, Juszczak E; Baby-OSCAR Collaborative Group. N Engl J Med. 2024 Jan 25;390(4):314-325. doi: 10.1056/NEJMoa2305582.PMID: 38265644 Clinical Trial.

Percutaneous Closure of the Patent Ductus Arteriosus in Infants ≤2 kg: IMPACT Registry Insights.

Bischoff AR, Kennedy KF, Backes CH, Sathanandam S, McNamara PJ.Pediatrics. 2023 Sep 1;152(3):e2023061460. doi: 10.1542/peds.2023-061460.PMID: 37529882

Trends in Procedural Closure of the Patent Ductus Arteriosus among Infants Born at 22 to 30 Weeks' Gestation.

Shah ZS, Clark RH, Patt HA, Backes CH Jr, Tolia VN.J Pediatr. 2023 Aug 31;263:113716. doi: 10.1016/j.jpeds.2023.113716. Online ahead of print.PMID: 37659585

EBNEO Commentary: Precision management of the patent ductus arteriosus in micropreemies.

Mitra S.Acta Paediatr. 2023 Sep;112(9):2018-2019. doi: 10.1111/apa.16853. Epub 2023 May 28.PMID: 37246268 No abstract available.

Impact of early screening echocardiography and targeted PDA treatment on neonatal outcomes in "22-23" week and "24-26" infants.

Giesinger RE, Hobson AA, Bischoff AR, Klein JM, McNamara PJ.Semin Perinatol. 2023 Mar;47(2):151721. doi: 10.1016/j.semperi.2023.151721. Epub 2023 Mar 5.PMID: 36882362

Use of Vasopressors in Extremely Preterm Infants in First Week of Life.

Zaveri PG, Walker AM, Upadhyay K, Talati AJ.Am J Perinatol. 2023 Apr;40(5):513-518. doi: 10.1055/s-0041-1729558. Epub 2021 May 14.PMID: 33990125

Impact of early screening echocardiography and targeted PDA treatment on neonatal outcomes in "22-23" week and "24-26" infants.

Giesinger RE, Hobson AA, Bischoff AR, Klein JM, McNamara PJ.Semin Perinatol. 2023 Mar;47(2):151721. doi: 10.1016/j.semperi.2023.151721. Epub 2023 Mar 5.PMID: 36882362

The dilemma of feeding during the treatment of patent ductus arteriosus with oral ibuprofen in preterm infants ≤30 weeks of gestation-a randomized controlled trial.

Kaur S, Manerkar S, Mondkar J, Kalamdani P, Patra S, Kalathingal T.J Perinatol. 2023 Feb;43(2):203-208. doi: 10.1038/s41372-022-01597-x. Epub 2023 Jan 5.PMID: 36604581 Clinical Trial.

Neurodevelopmental outcomes of preterm neonates receiving rescue inhaled nitric oxide in the first week of age: a cohort study.

Gurram Venkata SKR, Lodha A, Hicks M, Jain A, Lapointe A, Makary H, Kanungo J, Lee KS, Ye X, Shah PS, Soraisham AS; Canadian Neonatal Network and Canadian Neonatal Follow Up Network; Canadian Neonatal Network and Canadian Neonatal Follow Up NetworkTM.Arch Dis Child Fetal Neonatal Ed. 2023 Oct 27:fetalneonatal-2023-325418. doi: 10.1136/archdischild-2023-325418. Online ahead of print.PMID: 37890983

Diagnostic Yield of Exome Sequencing in Pediatric Cardiomyopathy.

Keisling J, Bedoukian E, Burstein DS, Gaynor JW, Gray C, Krantz I, Izumi K, Leonard J, Lin KY, Medne L, Seymour C, Skraban C, Ritter A, Ahrens-Nicklas RC.J Pediatr. 2023 Nov 1:113808. doi: 10.1016/j.jpeds.2023.113808. Online ahead of print.PMID: 37923198

Inhaled Nitric Oxide Therapy in the Post-Acute Phase in Extremely Preterm Infants: A Japanese Cohort Study.

Nakanishi H, Isayama T, Kokubo M, Hirano S, Kusuda S; Neonatal Research Network, Japan.J Pediatr. 2023 Jan;252:61-67.e5. doi: 10.1016/j.jpeds.2022.07.057. Epub 2022 Sep 16.PMID: 36116533

Effects of prophylactic indomethacin on morbidity and mortality in infants <25 weeks' gestation: a protocol driven intention to treat analysis.

Clyman RI, Hills NK.J Perinatol. 2022 Dec;42(12):1662-1668. doi: 10.1038/s41372-022-01547-7. Epub 2022 Oct 30.

Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants.

Jasani B, Mitra S, Shah PS.Cochrane Database Syst Rev. 2022 Dec 15;12:CD010061. doi: 10.1002/14651858.CD010061.pub5.

Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus.

Hundscheid T, Onland W, Kooi EMW, Vijlbrief DC, de Vries WB, Dijkman KP, van Kaam AH, Villamor E, Kroon AA, Visser R, Mulder-de Tollenaer SM, De Bisschop B, Dijk PH, Avino D, Hocq C, Zecic A, Meeus M, de Baat T, Derriks F, Henriksen TB, Kyng KJ, Donders R, Nuytemans DHGM, Van Overmeire B, Mulder AL, de Boode WP; BeNeDuctus Trial Investigators.N Engl J Med. 2023 Mar 16;388(11):980-990. doi: 10.1056/NEJMoa2207418. Epub 2022 Dec 6.

The use of milrinone in neonates with persistent pulmonary hypertension of the newborn - a randomised controlled trial pilot study (MINT 1): study protocol and review of literature.

El-Khuffash A, McNamara PJ, Breatnach C, Bussmann N, Smith A, Feeney O, Tully E, Griffin J, de Boode WP, Cleary B, Franklin O, Dempsey E.Matern Health Neonatol Perinatol. 2018 Dec 3;4:24. doi: 10.1186/s40748-018-0093-1. eCollection 2018.

Higher blood pressure in adolescent boys after very preterm birth and fetal growth restriction.

Liefke J, Steding-Ehrenborg K, Sjöberg P, Ryd D, Morsing E, Arheden H, Ley D, Hedström E.Pediatr Res. 2023 Jun;93(7):2019-2027. doi: 10.1038/s41390-022-02367-3. Epub 2022 Nov 7.

Randomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia.

Deprest JA, Nicolaides KH, Benachi A, Gratacos E, Ryan G, Persico N, Sago H, Johnson A, Wielgoś M, Berg C, Van Calster B, Russo FM; TOTAL Trial for Severe Hypoplasia Investigators.N Engl J Med. 2021 Jul 8;385(2):107-118. doi: 10.1056/NEJMoa2027030. Epub 2021 Jun 8.

Delayed Surgical Closure of the Patent Ductus Arteriosus: Does the Brain Pay the Price?

Lemmers P, Vijlbrief D, Benders M, Alderliesten T, Veldhuis M, Baerts W, Koopman-Esseboom C, Groenendaal F, van Bel F.J Pediatr. 2023 Mar;254:25-32. doi: 10.1016/j.jpeds.2022.10.010. Epub 2022 Oct 12.

Pulmonary Hypertension in Preterm Infants Treated With Laser vs Anti-Vascular Endothelial Growth Factor Therapy for Retinopathy of Prematurity.

Nitkin CR, Bamat NA, Lagatta J, DeMauro SB, Lee HC, Patel RM, King B, Slaughter JL, Campbell JP, Richardson T, Lewis T.JAMA Ophthalmol. 2022 Nov 1;140(11):1085-1094. doi: 10.1001/jamaophthalmol.2022.3788.

Lower pass threshold (≥93%) for critical congenital heart disease screening at high altitude prevents repeat screening and reduces false positives.

Sneeringer MR, Vadlaputi P, Lakshminrusimha S, Siefkes H.J Perinatol. 2022 Sep;42(9):1176-1182. doi: 10.1038/s41372-022-01491-6. Epub 2022 Aug 17.

The Clinical and Cost Utility of Cardiac Catheterizations in Infants with Bronchopulmonary Dysplasia.

Yang EL, Levy PT, Critser PJ, Dukhovny D, Evers PD.J Pediatr. 2022 Jul;246:56-63.e3. doi: 10.1016/j.jpeds.2022.04.009. Epub 2022 Apr 14.

Blood pressure values and hypotension management in extremely preterm infants: a multi-center study.

Peeples ES, Comstock BA, Heagerty PJ, Juul SE; Preterm Erythropoietin Neuroprotection (PENUT) Trial Investigators.J Perinatol. 2022 Sep;42(9):1169-1175. doi: 10.1038/s41372-022-01425-2. Epub 2022 Jun 17.

Outcomes after neonatal cardiac surgery: The impact of a dedicated neonatal cardiac program.

Goldshtrom N, Vasquez AM, Chaves DV, Bateman DA, Kalfa D, Levasseur S, Torres AJ, Bacha E, Krishnamurthy G.J Thorac Cardiovasc Surg. 2023 Jun;165(6):2204-2211.e4. doi: 10.1016/j.jtcvs.2022.06.013. Epub 2022 Jun 28.

Oral versus intravenous sildenafil for pulmonary hypertension in neonates: a randomized trial.

Chetan C, Suryawanshi P, Patnaik S, Soni NB, Rath C, Pareek P, Gupta B, Garegrat R, Verma A, Singh Y.BMC Pediatr. 2022 May 27;22(1):311. doi: 10.1186/s12887-022-03366-3.

Recognition and Management of Cardiovascular Insufficiency in the Very Low Birth Weight Newborn.

Goldsmith JP, Keels E.Pediatrics. 2022 Mar 1;149(3):e2021056051. doi: 10.1542/peds.2021-056051.

Prophylactic cyclo-oxygenase inhibitor drugs for the prevention of morbidity and mortality in preterm infants: a network meta-analysis.

Mitra S, Gardner CE, MacLellan A, Disher T, Styranko DM, Campbell-Yeo M, Kuhle S, Johnston BC, Dorling J.Cochrane Database Syst Rev. 2022 Apr 1;4(4):CD013846. doi: 10.1002/14651858.CD013846.pub2.

The impact of a PDA on tissue oxygenation and haemodynamics following a blood transfusion in preterm infants.

Smith A, Armstrong S, Dempsey E, El-Khuffash A.Pediatr Res. 2023 Apr;93(5):1314-1320. doi: 10.1038/s41390-022-01967-3. Epub 2022 Feb 12.

Impact of Carbon Dioxide on Cerebral Oxygenation and Vital Parameters in Stable Preterm and Term Infants Immediately after Birth.

Wolfsberger CH, Bruckner M, Schwaberger B, Mileder LP, Urlesberger B, Pichler G.Neonatology. 2022;119(1):10-17. doi: 10.1159/000519636. Epub 2021 Oct 28.

Oral versus intravenous paracetamol for patent ductus arteriosus closure in preterm infants.

Gover A, Levy PT, Rotschild A, Golzman M, Molad M, Lavie-Nevo K, Kessel I.Pediatr Res. 2022 Oct;92(4):1146-1152. doi: 10.1038/s41390-022-01944-w. Epub 2022 Jan 27.

Association of umbilical cord blood gas values with mortality and severe neurologic injury in preterm neonates <29 weeks' gestation: a national cohort study.

Shah PS, Barrett J, Claveau M, Cieslak Z, Makary H, Monterrosa L, Sherlock R, Yang J, McDonald SD; Canadian Neonatal Network; Canadian Preterm Birth Network Investigators.Am J Obstet Gynecol. 2022 Jul;227(1):85.e1-85.e10. doi: 10.1016/j.ajog.2022.01.001. Epub 2022 Jan 6.

Early arterial pressure monitoring and term-equivalent age MRI findings in very preterm infants.

Butticci R, Habre C, Hernandez A, Barcos-Munoz F, Pfister R, Hanquinet S, Beuchée A, Baud O.Pediatr Res. 2022 Sep;92(3):822-828. doi: 10.1038/s41390-021-01839-2. Epub 2021 Nov 19.

Is late treatment with acetaminophen safe and effective in avoiding surgical ligation among extremely preterm neonates with persistent patent ductus arteriosus?

https://www.nature.com/articles/s41372-021-01194-4

Cardiac Performance in the First Year of Age Among Preterm Infants Fed Maternal Breast Milk. https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2783546

Patent ductus arteriosus shunt elimination results in a reduction in adverse outcomes: a post hoc analysis of the PDA RCT cohort. https://www.nature.com/articles/s41372-021-01002-z

Comparison of standard versus high-dose ibuprofen for the treatment of hemodynamically significant patent ductus arteriosus in preterm infants.

https://www.nature.com/articles/s41372-021-01046-1

Effect of Early Targeted Treatment of Ductus Arteriosus with Ibuprofen

https://www.jpeds.com/article/S0022-3476(20)31488-8/fulltext

Outcomes of Extremely Premature Infants Comparing PDA Management Approaches.

https://www.jpeds.com/article/S0022-3476(21)00335-8/fulltext

Changes in PDA Treatment Strategy and Respiratory Outcomes

https://www.jpeds.com/article/S0022-3476(21)00356-5/fulltext