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Infectious Disease

📑 Journal Club Articles

Chorioamnionitis and Two-Year Outcomes in Infants with Hypoxic-Ischemic Encephalopathy.

Cornet MC, Gonzalez FF, Glass HC, Wu TW, Wisnowski JL, Li Y, Heagerty P, Juul SE, Wu YW.J Pediatr. 2024 Nov 20:114415. doi: 10.1016/j.jpeds.2024.114415. Online ahead of print.PMID: 39577760

Blood volume collected for cultures in infants with suspected neonatal sepsis.

Rueda MS, Soghier L, Campos J, Bahar B, Bost JE, Gai J, Hamdy RF.J Perinatol. 2024 Sep 28. doi: 10.1038/s41372-024-02120-0. Online ahead of print.PMID: 39341980

Don't wait, vaccinate: evaluation of routine vaccination administration and reactogenicity in preterm infants.

Abdelmessih E, Desai PV, Tracy J, Papadopoulos J, Bashqoy F.J Perinatol. 2024 Sep 10. doi: 10.1038/s41372-024-02111-1. Online ahead of print.PMID: 39256613

Mpox in Pregnancy - Risks, Vertical Transmission, Prevention, and Treatment.

Nachega JB, Mohr EL, Dashraath P, Mbala-Kingebeni P, Anderson JR, Myer L, Gandhi M, Baud D, Mofenson LM, Muyembe-Tamfum JJ; Mpox Research Consortium (MpoxReC).N Engl J Med. 2024 Aug 28. doi: 10.1056/NEJMp2410045. Online ahead of print.PMID: 39197097 No abstract available.

Neonatal Monkeypox Virus Infection.

Ramnarayan P, Mitting R, Whittaker E, Marcolin M, O'Regan C, Sinha R, Bennett A, Moustafa M, Tickner N, Gilchrist M, Kershaw A, Rampling T; NHS England High Consequence Infectious Diseases (Airborne) Network.N Engl J Med. 2022 Oct 27;387(17):1618-1620. doi: 10.1056/NEJMc2210828. Epub 2022 Oct 12.PMID: 36223535 No abstract available.

Early Antibiotic Exposure and Bronchopulmonary Dysplasia in Very Preterm Infants at Low Risk of Early-Onset Sepsis.

Shi W, Chen Z, Shi L, Jiang S, Zhou J, Gu X, Lei X, Xiao T, Zhu Y, Qian A, Zhou W, Lee SK, Du L, Yang J, Ma X, Hu L; Chinese Neonatal Network.JAMA Netw Open. 2024 Jun 3;7(6):e2418831. doi: 10.1001/jamanetworkopen.2024.18831.PMID: 38935376 Free PMC article.

Trends in C-Reactive Protein Use in Early-Onset Sepsis Evaluations and Associated Antibiotic Use.

Barboza AZ, Flannery DD, Shu D, Galloway M, Dhudasia MB, Bonafide CP, Benitz WE, Gerber JS, Mukhopadhyay S.J Pediatr. 2024 Jun 18:114153. doi: 10.1016/j.jpeds.2024.114153. Online ahead of print.PMID: 38901777

Autism Spectrum Disorder Diagnoses and Congenital Cytomegalovirus. 

Pesch MH, Leung J, Lanzieri TM, Tinker SC, Rose CE, Danielson ML, Yeargin-Allsopp M, Grosse SD.Pediatrics. 2024 May 29:e2023064081. doi: 10.1542/peds.2023-064081. Online ahead of print.PMID: 38808409

Infant Feeding for Persons Living With and at Risk for HIV in the United States: Clinical Report. 

Abuogi L, Noble L, Smith C; COMMITTEE ON PEDIATRIC AND ADOLESCENT HIV; SECTION ON BREASTFEEDING.Pediatrics. 2024 May 20:e2024066843. doi: 10.1542/peds.2024-066843. Online ahead of print.PMID: 38766700

Factors influencing C-reactive protein status on admission in neonates after birth.

Cao C, Wang S, Liu Y, Yue S, Wang M, Yu X, Ding Y, Lv M, Fang K, Chu M, Liao Z.BMC Pediatr. 2024 Feb 1;24(1):89. doi: 10.1186/s12887-024-04583-8.PMID: 38302903 Free PMC article.

Positioning for lumbar puncture in newborn infants. 

Pessano S, Bruschettini M, Prescott MG, Romantsik O.Cochrane Database Syst Rev. 2023 Dec 14;12(12):CD015592. doi: 10.1002/14651858.CD015592.pub3.PMID: 38096386 Review.

Short-course antibiotic therapy for pneumonia in the neonatal intensive care unit.

Lewald ZS, Prusakov P, Magers JK, Kielt MJ, de Alba Romero C, White NO, Miller RR, Moraille R, Theile AR, Sánchez PJ; Nationwide Children’s Hospital Neonatal Antimicrobial Stewardship Program (NEO-ASP).J Perinatol. 2023 Sep;43(9):1145-1151. doi: 10.1038/s41372-023-01720-6. Epub 2023 Jul 12.PMID: 37438484

Antibiotic Prophylaxis in Infants with Grade III, IV, or V Vesicoureteral Reflux.

Morello W, Baskin E, Jankauskiene A, Yalcinkaya F, Zurowska A, Puccio G, Serafinelli J, La Manna A, Krzemień G, Pennesi M, La Scola C, Becherucci F, Brugnara M, Yuksel S, Mekahli D, Chimenz R, De Palma D, Zucchetta P, Vajauskas D, Drozdz D, Szczepanska M, Caliskan S, Lombet J, Minoli DG, Guarino S, Gulleroglu K, Ruzgiene D, Szmigielska A, Barbi E, Ozcakar ZB, Kranz A, Pasini A, Materassi M, De Rechter S, Ariceta G, Weber LT, Marzuillo P, Alberici I, Taranta-Janusz K, Caldas Afonso A, Tkaczyk M, Català M, Cabrera Sevilla JE, Mehls O, Schaefer F, Montini G; PREDICT Study Group.N Engl J Med. 2023 Sep 14;389(11):987-997. doi: 10.1056/NEJMoa2300161. Epub 2023 Sep 12.PMID: 37702442 Clinical Trial.

Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants.

Kampmann B, Madhi SA, Munjal I, Simões EAF, Pahud BA, Llapur C, Baker J, Pérez Marc G, Radley D, Shittu E, Glanternik J, Snaggs H, Baber J, Zachariah P, Barnabas SL, Fausett M, Adam T, Perreras N, Van Houten MA, Kantele A, Huang LM, Bont LJ, Otsuki T, Vargas SL, Gullam J, Tapiero B, Stein RT, Polack FP, Zar HJ, Staerke NB, Duron Padilla M, Richmond PC, Koury K, Schneider K, Kalinina EV, Cooper D, Jansen KU, Anderson AS, Swanson KA, Gruber WC, Gurtman A; MATISSE Study Group.N Engl J Med. 2023 Apr 20;388(16):1451-1464. doi: 10.1056/NEJMoa2216480. Epub 2023 Apr 5.PMID: 37018474 Clinical Trial.

Short-course empiric antibiotic therapy for possible early-onset sepsis in the NICU.

Sánchez PJ, Prusakov P, de Alba Romero C, Zamora-Flores E, Reyes Escamilla MC, White NO, Miller RR, Moraille R, Theile AR, Magers JK; Nationwide Children’s Hospital Neonatal Antimicrobial Stewardship Program (NEO-ASP).J Perinatol. 2023 Jun;43(6):741-745. doi: 10.1038/s41372-023-01634-3. Epub 2023 Feb 22.PMID: 36813903

Viral Infections and Neonatal Necrotizing Enterocolitis: A Meta-analysis.

Mani S, Hazra S, Hagan J, Sisson A, Nair J, Pammi M.Pediatrics. 2023 Jul 1;152(1):e2022060876. doi: 10.1542/peds.2022-060876.PMID: 37293714

Empirical Antimicrobial Therapy of Neonates with Necrotizing Enterocolitis: A Systematic Review.

Donà D, Gastaldi A, Barbieri E, Bonadies L, Aluvaala J, English M.Am J Perinatol. 2023 Apr;40(6):646-656. doi: 10.1055/s-0041-1730364. Epub 2021 Jun 14.PMID: 34126646 Free PMC article.

Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants.

Kampmann B, Madhi SA, Munjal I, Simões EAF, Pahud BA, Llapur C, Baker J, Pérez Marc G, Radley D, Shittu E, Glanternik J, Snaggs H, Baber J, Zachariah P, Barnabas SL, Fausett M, Adam T, Perreras N, Van Houten MA, Kantele A, Huang LM, Bont LJ, Otsuki T, Vargas SL, Gullam J, Tapiero B, Stein RT, Polack FP, Zar HJ, Staerke NB, Duron Padilla M, Richmond PC, Koury K, Schneider K, Kalinina EV, Cooper D, Jansen KU, Anderson AS, Swanson KA, Gruber WC, Gurtman A; MATISSE Study Group.N Engl J Med. 2023 Apr 20;388(16):1451-1464. doi: 10.1056/NEJMoa2216480. Epub 2023 Apr 5.PMID: 37018474 Clinical Trial.

Azithromycin to Prevent Sepsis or Death in Women Planning a Vaginal Birth.

Tita ATN, Carlo WA, McClure EM, Mwenechanya M, Chomba E, Hemingway-Foday JJ, Kavi A, Metgud MC, Goudar SS, Derman R, Lokangaka A, Tshefu A, Bauserman M, Bose C, Shivkumar P, Waikar M, Patel A, Hibberd PL, Nyongesa P, Esamai F, Ekhaguere OA, Bucher S, Jessani S, Tikmani SS, Saleem S, Goldenberg RL, Billah SM, Lennox R, Haque R, Petri W, Figueroa L, Mazariegos M, Krebs NF, Moore JL, Nolen TL, Koso-Thomas M; A-PLUS Trial Group.N Engl J Med. 2023 Mar 30;388(13):1161-1170. doi: 10.1056/NEJMoa2212111. Epub 2023 Feb 9.PMID: 36757318 Clinical Trial.

Current pain management practices for preterm infants with necrotizing enterocolitis: a European survey.

Ten Barge JA, van den Bosch GE, Meesters NJ, Allegaert K, Arribas C, Cavallaro G, Garrido F, Raffaeli G, Vermeulen MJ, Simons SHP; ESPR Special Interest Group for Neonatal Pain and the NEC Pain Study Group.Pediatr Res. 2023 Aug;94(2):555-563. doi: 10.1038/s41390-023-02508-2. Epub 2023 Feb 24.PMID: 36828969 Free PMC article.

Predictors of the Outcome at 2 Years in Neonates With Congenital Cytomegalovirus Infection.

Fourgeaud J, Magny JF, Couderc S, Garcia P, Maillotte AM, Benard M, Pinquier D, Minodier P, Astruc D, Patural H, Parat S, Guillois B, Garenne A, Guilleminot T, Parodi M, Bussières L, Ghout I, Ville Y, Leruez-Ville M.Pediatrics. 2024 Mar 15:e2023063531. doi: 10.1542/peds.2023-063531. Online ahead of print.PMID: 38487823

Potential for Maternally Administered Vaccine for Infant Group B Streptococcus.

Madhi SA, Anderson AS, Absalon J, Radley D, Simon R, Jongihlati B, Strehlau R, van Niekerk AM, Izu A, Naidoo N, Kwatra G, Ramsamy Y, Said M, Jones S, Jose L, Fairlie L, Barnabas SL, Newton R, Munson S, Jefferies Z, Pavliakova D, Silmon de Monerri NC, Gomme E, Perez JL, Scott DA, Gruber WC, Jansen KU.N Engl J Med. 2023 Jul 20;389(3):215-227. doi: 10.1056/NEJMoa2116045.PMID: 37467497 Clinical Trial

Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants.

Hammitt LL, Dagan R, Yuan Y, Baca Cots M, Bosheva M, Madhi SA, Muller WJ, Zar HJ, Brooks D, Grenham A, Wählby Hamrén U, Mankad VS, Ren P, Takas T, Abram ME, Leach A, Griffin MP, Villafana T; MELODY Study Group.N Engl J Med. 2022 Mar 3;386(9):837-846. doi: 10.1056/NEJMoa2110275.PMID: 35235726 Clinical Trial.

Umbilical cord blood culture for early onset sepsis in preterm infants.

Bensouda B, Mandel R, Altit G, Ali N.Pediatr Res. 2024 Apr 15. doi: 10.1038/s41390-024-03183-7. Online ahead of print.PMID: 38622259

Maternal syphilis rates tripled in the US between 2016 and 2022, data show.

Tanne JH.BMJ. 2024 Feb 15;384:q416. doi: 10.1136/bmj.q416.PMID: 38359912 No abstract available.

Neonatal Outcomes After COVID-19 Vaccination in Pregnancy.

Norman M, Magnus MC, Söderling J, Juliusson PB, Navér L, Örtqvist AK, Håberg S, Stephansson O.JAMA. 2024 Feb 6;331(5):396-407. doi: 10.1001/jama.2023.26945.PMID: 38319332

Azithromycin during Routine Well-Infant Visits to Prevent Death.

Sié A, Ouattara M, Bountogo M, Boudo V, Ouedraogo T, Compaoré G, Dah C, Bagagnan C, Lebas E, Hu H, Rice J, Porco TC, Arnold BF, Lietman TM, Oldenburg CE.N Engl J Med. 2024 Jan 18;390(3):221-229. doi: 10.1056/NEJMoa2309495.PMID: 38231623 Clinical Trial.

Clinical Chorioamnionitis and Neurodevelopment at 5 Years of Age in Children Born Preterm: The EPIPAGE-2 Cohort Study. 

Salmon Rm F, Kayem G, Maisonneuve E, Foix-L'Hélias L, Benhammou V, Kaminski M, Marchand-Martin L, Kana G, Subtil D, Lorthe Rm E, Ancel PY, Letouzey M; EPIPAGE-2 Infectious diseases working group.J Pediatr. 2024 Jan 17:113921. doi: 10.1016/j.jpeds.2024.113921. Online ahead of print.PMID: 38242316 Free article.

Nirsevimab for Prevention of Hospitalizations Due to RSV in Infants.

Drysdale SB, Cathie K, Flamein F, Knuf M, Collins AM, Hill HC, Kaiser F, Cohen R, Pinquier D, Felter CT, Vassilouthis NC, Jin J, Bangert M, Mari K, Nteene R, Wague S, Roberts M, Tissières P, Royal S, Faust SN; HARMONIE Study Group.N Engl J Med. 2023 Dec 28;389(26):2425-2435. doi: 10.1056/NEJMoa2309189.PMID: 38157500 Clinical Trial.

Perinatal risk factors for neonatal early-onset sepsis: a meta-analysis of observational studies.

Guo L, Han W, Su Y, Wang N, Chen X, Ma J, Liang J, Hao L, Ren C.J Matern Fetal Neonatal Med. 2023 Dec;36(2):2259049. doi: 10.1080/14767058.2023.2259049. Epub 2023 Sep 24.PMID: 37743349 Free article.

Potential for Maternally Administered Vaccine for Infant Group B Streptococcus.

Madhi SA, Anderson AS, Absalon J, Radley D, Simon R, Jongihlati B, Strehlau R, van Niekerk AM, Izu A, Naidoo N, Kwatra G, Ramsamy Y, Said M, Jones S, Jose L, Fairlie L, Barnabas SL, Newton R, Munson S, Jefferies Z, Pavliakova D, Silmon de Monerri NC, Gomme E, Perez JL, Scott DA, Gruber WC, Jansen KU.N Engl J Med. 2023 Jul 20;389(3):215-227. doi: 10.1056/NEJMoa2116045.PMID: 37467497 Clinical Trial.

Early Antibiotic Use and Neonatal Outcomes Among Preterm Infants Without Infections.

Yu W, Zhang L, Li S, Yan W, Bai R, Yang Z, Shi J, Yuan J, Yang C, Cai W, Wang Y, Zhang Y, Gu X, Cao X, Huang Y, Hong L, Zhou Q, Yang Y, Lee SK, Jiang S, Cao Y; Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality (REIN-EPIQ) Study Group.Pediatrics. 2023 May 1;151(5):e2022059427. doi: 10.1542/peds.2022-059427.PMID: 37042203

Diagnostic Performance and Patient Outcomes With C-Reactive Protein Use in Early-Onset Sepsis Evaluations.

Dhudasia MB, Benitz WE, Flannery DD, Christ L, Rub D, Remaschi G, Puopolo KM, Mukhopadhyay S.J Pediatr. 2023 May;256:98-104.e6. doi: 10.1016/j.jpeds.2022.12.007. Epub 2022 Dec 16.

Incidence of and Neurodevelopmental Outcomes After Late-Onset Meningitis Among Children Born Extremely Preterm.

Brumbaugh JE, Bell EF, Do BT, Greenberg RG, Stoll BJ, DeMauro SB, Harmon HM, Hintz SR, Das A, Puopolo KM; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.JAMA Netw Open. 2022 Dec 1;5(12):e2245826. doi: 10.1001/jamanetworkopen.2022.45826.

Targeted screening for congenital cytomegalovirus infection: clinical, audiological and neuroimaging findings.

Chung PK, Schornagel F, Oudesluys-Murphy AM, de Vries LS, Soede W, van Zwet E, Vossen A.Arch Dis Child Fetal Neonatal Ed. 2023 May;108(3):302-308. doi: 10.1136/archdischild-2022-324699. Epub 2022 Dec 22.

Adverse effects of COVID-19 pandemic on a multicenter randomized controlled trial.

Abu Jawdeh EG, Hunt CE, Eichenwald E, Corwin MJ, McEntire B, Heeren T, Crowell LM, Ikponmwonba C, Saroufim A, Kerr S; ICAF Study Group.J Perinatol. 2023 May;43(5):653-658. doi: 10.1038/s41372-022-01592-2. Epub 2022 Dec 29.

Late-Onset Sepsis Among Very Preterm Infants.

Flannery DD, Edwards EM, Coggins SA, Horbar JD, Puopolo KM.Pediatrics. 2022 Dec 1;150(6):e2022058813. doi: 10.1542/peds.2022-058813.

Variability in antibiotic duration for necrotizing enterocolitis and outcomes in a large multicenter cohort.

Ahmad I, Premkumar MH, Hair AB, Sullivan KM, Zaniletti I, Sharma J, Nayak SP, Reber KM, Padula M, Brozanski B, DiGeronimo R, Yanowitz TD; Children’s Hospitals Neonatal Consortium NEC Focus Group.J Perinatol. 2022 Nov;42(11):1458-1464. doi: 10.1038/s41372-022-01433-2. Epub 2022 Jun 27.

Evolving antibiotic resistance in Group B Streptococci causing invasive infant disease: 1970-2021.

Sabroske EM, Iglesias MAS, Rench M, Moore T, Harvey H, Edwards M, Baker CJ, Flores AR.Pediatr Res. 2023 Jun;93(7):2067-2071. doi: 10.1038/s41390-022-02375-3. Epub 2022 Nov 9.

Early skin-to-skin contact and risk of late-onset-sepsis in very and extremely preterm infants.

Le Ray I, Kuhn P, Letouzey M, Roué JM, Mitha A, Glorieux I, Foix-L'Hélias L, Marchand-Martin L, Ancel PY, Kaminski M, Pierrat V; Epipage 2 Neurodevelopmental care writing Group; EPIPAGE-2 Infectious diseases writing group.Pediatr Res. 2023 Jun;93(7):2091-2100. doi: 10.1038/s41390-022-02383-3. Epub 2022 Nov 14.

Initial Laparotomy Versus Peritoneal Drainage in Extremely Low Birthweight Infants With Surgical Necrotizing Enterocolitis or Isolated Intestinal Perforation: A Multicenter Randomized Clinical Trial.

Blakely ML, Tyson JE, Lally KP, Hintz SR, Eggleston B, Stevenson DK, Besner GE, Das A, Ohls RK, Truog WE, Nelin LD, Poindexter BB, Pedroza C, Walsh MC, Stoll BJ, Geller R, Kennedy KA, Dimmitt RA, Carlo WA, Cotten CM, Laptook AR, Van Meurs KP, Calkins KL, Sokol GM, Sanchez PJ, Wyckoff MH, Patel RM, Frantz ID 3rd, Shankaran S, D'Angio CT, Yoder BA, Bell EF, Watterberg KL, Martin CA, Harmon CM, Rice H, Kurkchubasche AG, Sylvester K, Dunn JCY, Markel TA, Diesen DL, Bhatia AM, Flake A, Chwals WJ, Brown R, Bass KD, St Peter SD, Shanti CM, Pegoli W Jr, Skarda D, Shilyansky J, Lemon DG, Mosquera RA, Peralta-Carcelen M, Goldstein RF, Vohr BR, Purdy IB, Hines AC, Maitre NL, Heyne RJ, DeMauro SB, McGowan EC, Yolton K, Kilbride HW, Natarajan G, Yost K, Winter S, Colaizy TT, Laughon MM, Lakshminrusimha S, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health, Human Development Neonatal Research Network.Ann Surg. 2021 Oct 1;274(4):e370-e380. doi: 10.1097/SLA.0000000000005099.

Effect of Treating Parents Colonized With Staphylococcus aureus on Transmission to Neonates in the Intensive Care Unit: A Randomized Clinical Trial.

Milstone AM, Voskertchian A, Koontz DW, Khamash DF, Ross T, Aucott SW, Gilmore MM, Cosgrove SE, Carroll KC, Colantuoni E.JAMA. 2020 Jan 28;323(4):319-328. doi: 10.1001/jama.2019.20785.

Predicting the likelihood of lower respiratory tract Ureaplasma infection in preterms.

Viscardi RM, Magder LS, Terrin ML, Davis NL.Arch Dis Child Fetal Neonatal Ed. 2023 May;108(3):250-255. doi: 10.1136/archdischild-2022-324192. Epub 2022 Oct 19.

Long-Term Outcome of Necrotizing Enterocolitis and Spontaneous Intestinal Perforation.

Vaidya R, Yi JX, O'Shea TM, Jensen ET, Joseph RM, Shenberger J, Gogcu S, Wagner K, Msall ME, Thompson AL, Frazier JA, Fry R, Singh R; ELGAN-ECHO Study Investigators.Pediatrics. 2022 Nov 1;150(5):e2022056445. doi: 10.1542/peds.2022-056445.

Efficacy and safety of switching from intravenous to oral antibiotics (amoxicillin-clavulanic acid) versus a full course of intravenous antibiotics in neonates with probable bacterial infection (RAIN): a multicentre, randomised, open-label, non-inferiority trial.

Keij FM, Kornelisse RF, Hartwig NG, van der Sluijs-Bens J, van Beek RHT, van Driel A, van Rooij LGM, van Dalen-Vink I, Driessen GJA, Kenter S, von Lindern JS, Eijkemans M, Stam-Stigter GM, Qi H, van den Berg MM, Baartmans MGA, van der Meer-Kappelle LH, Meijssen CB, Norbruis OF, Heidema J, van Rossem MC, den Butter PCP, Allegaert K, Reiss IKM, Tramper-Stranders GA.Lancet Child Adolesc Health. 2022 Nov;6(11):799-809. doi: 10.1016/S2352-4642(22)00245-0. Epub 2022 Sep 9.

A comparison of bacterial colonization between nasogastric and orogastric enteral feeding tubes in infants in the neonatal intensive care unit.

Vongbhavit K, Salinero LK, Kalanetra KM, Masarweh C, Yu A, Taft DH, Mills DA, Underwood MA.J Perinatol. 2022 Nov;42(11):1446-1452. doi: 10.1038/s41372-022-01452-z. Epub 2022 Jul 15.

Dual-site blood culture yield and time to positivity in neonatal late-onset sepsis.

Coggins SA, Harris MC, Srinivasan L.Arch Dis Child Fetal Neonatal Ed. 2022 Sep;107(5):475-480. doi: 10.1136/archdischild-2021-322844. Epub 2021 Nov 9.

Epidemiology of Neonatal COVID-19 in the United States.

Devin J, Marano R, Mikhael M, Feaster W, Sanger T, Ehwerhemuepha L.Pediatrics. 2022 Oct 1;150(4):e2022056297. doi: 10.1542/peds.2022-056297.

Remote ischaemic conditioning in necrotising enterocolitis: a phase I feasibility and safety study.

Zozaya C, Ganji N, Li B, Janssen Lok M, Lee C, Koike Y, Gauda E, Offringa M, Eaton S, Shah PS, Pierro A.Arch Dis Child Fetal Neonatal Ed. 2023 Jan;108(1):69-76. doi: 10.1136/archdischild-2022-324174. Epub 2022 Aug 8.

Ampicillin dosing in premature infants for early-onset sepsis: exposure-driven efficacy, safety, and stewardship.

Le J, Greenberg RG, Yoo Y, Clark RH, Benjamin DK Jr, Zimmerman KO, Cohen-Wolkowiez M, Wade KC; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee.J Perinatol. 2022 Jul;42(7):959-964. doi: 10.1038/s41372-022-01344-2. Epub 2022 Feb 24.

Antimicrobial utilization in very-low-birth-weight infants: association with probiotic use.

Ting JY, Yoon EW, Fajardo CA, Daboval T, Bertelle V, Shah PS; Canadian Neonatal Network (CNN) Investigators.J Perinatol. 2022 Jul;42(7):947-952. doi: 10.1038/s41372-022-01382-w. Epub 2022 Apr 11.

Antibiotic exposure prevents acquisition of beneficial metabolic functions in the preterm infant gut microbiome.

Xu Y, Milburn O, Beiersdorfer T, Du L, Akinbi H, Haslam DB.Microbiome. 2022 Jul 7;10(1):103. doi: 10.1186/s40168-022-01300-4.

COVID-19 Vaccines in Infants, Children, and Adolescents.

COMMITTEE ON INFECTIOUS DISEASES.Pediatrics. 2022 Sep 1;150(3):e2022058700. doi: 10.1542/peds.2022-058700.

Multisystemic Inflammatory Syndrome in Neonates: A Systematic Review.

Shaiba LA, More K, Hadid A, Almaghrabi R, Al Marri M, Alnamnakani M, Shah P.Neonatology. 2022;119(4):405-417. doi: 10.1159/000524202. Epub 2022 May 5.

Early Antibiotic Exposure and Adverse Outcomes in Very Preterm Infants at Low Risk of Early-Onset Sepsis: The EPIPAGE-2 Cohort Study.

Letouzey M, Lorthe E, Marchand-Martin L, Kayem G, Charlier C, Butin M, Mitha A, Kaminski M, Benhammou V, Ancel PY, Boileau P, Foix-L'Hélias L; EPIPAGE-2 Infectious Diseases Working Group.J Pediatr. 2022 Apr;243:91-98.e4. doi: 10.1016/j.jpeds.2021.11.075. Epub 2021 Dec 21.

Presepsin for the Diagnosis of Neonatal Early-Onset Sepsis: A Systematic Review and Meta-analysis.

Poggi C, Lucenteforte E, Petri D, De Masi S, Dani C.JAMA Pediatr. 2022 Aug 1;176(8):750-758. doi: 10.1001/jamapediatrics.2022.1647.

Effect of antibiotics in the first week of life on faecal microbiota development.

Van Daele E, Kamphorst K, Vlieger AM, Hermes G, Milani C, Ventura M, Belzer C, Smidt H, van Elburg RM, Knol J.Arch Dis Child Fetal Neonatal Ed. 2022 May 9;107(6):603-10. doi: 10.1136/archdischild-2021-322861. Online ahead of print.

Safety and Efficacy of Nafcillin for Empiric Therapy of Late-Onset Sepsis in the NICU.

Magers J, Prusakov P, Speaks S, Conroy S, Sánchez PJ.Pediatrics. 2022 May 1;149(5):e2021052360. doi: 10.1542/peds.2021-052360.

Rapid Point-of-Care Genotyping to Avoid Aminoglycoside-Induced Ototoxicity in Neonatal Intensive Care.

McDermott JH, Mahaveer A, James RA, Booth N, Turner M, Harvey KE, Miele G, Beaman GM, Stoddard DC, Tricker K, Corry RJ, Garlick J, Ainsworth S, Beevers T, Bruce IA, Body R, Ulph F, MacLeod R, Roberts PL, Wilson PM, Newman WG; PALOH Study Team.JAMA Pediatr. 2022 May 1;176(5):486-492. doi: 10.1001/jamapediatrics.2022.0187.

Time to positivity of blood cultures in neonatal late-onset bacteraemia.

Mukhopadhyay S, Briker SM, Flannery DD, Dhudasia MB, Coggins SA, Woodford E, Walsh EM, Li S, Puopolo KM, Kuzniewicz MW.Arch Dis Child Fetal Neonatal Ed. 2022 Nov;107(6):583-588. doi: 10.1136/archdischild-2021-323416. Epub 2022 Mar 10.

Bifidobacteriumlongum subsp. infantis EVC001 Administration Is Associated with a Significant Reduction in the Incidence of Necrotizing Enterocolitis in Very Low Birth Weight Infants.

Tobias J, Olyaei A, Laraway B, Jordan BK, Dickinson SL, Golzarri-Arroyo L, Fialkowski E, Owora A, Scottoline B.J Pediatr. 2022 May;244:64-71.e2. doi: 10.1016/j.jpeds.2021.12.070. Epub 2022 Jan 12.

Glycerin Suppositories and Enemas in Premature Infants: A Meta-analysis.

Burchard PR, Lay R, Ruffolo LI, Ramazani SN, Walton JM, Livingston MH.Pediatrics. 2022 Apr 1;149(4):e2021053413. doi: 10.1542/peds.2021-053413.

Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants.

Griffin MP, Yuan Y, Takas T, Domachowske JB, Madhi SA, Manzoni P, Simões EAF, Esser MT, Khan AA, Dubovsky F, Villafana T, DeVincenzo JP; Nirsevimab Study Group.N Engl J Med. 2020 Jul 30;383(5):415-425. doi: 10.1056/NEJMoa1913556.

Use of Cotton Balls in Diapers for Collection of Urine Samples Impacts the Analysis of Routine Chemistry Tests: An Evaluation of Cotton Balls, Diapers, and Chemistry Analyzers.

Thomas SN, Stieglitz HM, Hackenmueller S, Suh-Lailam B, Pyle-Eilola AL.J Pediatr. 2022 Jun;245:179-183.e8. doi: 10.1016/j.jpeds.2022.02.051. Epub 2022 Mar 3.

Safety of Nirsevimab for RSV in Infants with Heart or Lung Disease or Prematurity.

Domachowske J, Madhi SA, Simões EAF, Atanasova V, Cabañas F, Furuno K, Garcia-Garcia ML, Grantina I, Nguyen KA, Brooks D, Chang Y, Leach A, Takas T, Yuan Y, Griffin MP, Mankad VS, Villafana T; MEDLEY Study Group.N Engl J Med. 2022 Mar 3;386(9):892-894. doi: 10.1056/NEJMc2112186.

Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants.

Hammitt LL, Dagan R, Yuan Y, Baca Cots M, Bosheva M, Madhi SA, Muller WJ, Zar HJ, Brooks D, Grenham A, Wählby Hamrén U, Mankad VS, Ren P, Takas T, Abram ME, Leach A, Griffin MP, Villafana T; MELODY Study Group.N Engl J Med. 2022 Mar 3;386(9):837-846. doi: 10.1056/NEJMoa2110275.

Risks of Infectious Diseases in Newborns Exposed to Alternative Perinatal Practices.

Nolt D, O'Leary ST, Aucott SW.Pediatrics. 2022 Feb 1;149(2):e2021055554. doi: 10.1542/peds.2021-055554.

Association of Birth During the COVID-19 Pandemic With Neurodevelopmental Status at 6 Months in Infants With and Without In Utero Exposure to Maternal SARS-CoV-2 Infection.

Shuffrey LC, Firestein MR, Kyle MH, Fields A, Alcántara C, Amso D, Austin J, Bain JM, Barbosa J, Bence M, Bianco C, Fernández CR, Goldman S, Gyamfi-Bannerman C, Hott V, Hu Y, Hussain M, Factor-Litvak P, Lucchini M, Mandel A, Marsh R, McBrian D, Mourad M, Muhle R, Noble KG, Penn AA, Rodriguez C, Sania A, Silver WG, O'Reilly KC, Stockwell M, Tottenham N, Welch MG, Zork N, Fifer WP, Monk C, Dumitriu D.JAMA Pediatr. 2022 Jun 1;176(6):e215563. doi: 10.1001/jamapediatrics.2021.5563. Epub 2022 Jun 6.

STORCH Infections Among Very Low Birth Weight and Preterm Infants: 2018-2020.

Edwards EM, Greenberg LT, Ehret DEY, Soll RF, Lanzieri TM, Horbar JD.Pediatrics. 2022 Jan 1;149(1):e2021053655. doi: 10.1542/peds.2021-053655.

A Proposed Framework for the Clinical Management of Neonatal "Culture-Negative" Sepsis.

Cantey JB, Prusakov P.J Pediatr. 2022 May;244:203-211. doi: 10.1016/j.jpeds.2022.01.006. Epub 2022 Jan 22.

Delivery Characteristics and the Risk of Early-Onset Neonatal Sepsis.

Flannery DD, Mukhopadhyay S, Morales KH, Dhudasia MB, Passarella M, Gerber JS, Puopolo KM.Pediatrics. 2022 Feb 1;149(2):e2021052900. doi: 10.1542/peds.2021-052900.

Neonatal early-onset infections: Comparing the sensitivity of the neonatal early-onset sepsis calculator to the Dutch and the updated NICE guidelines in an observational cohort of culture-positive cases.

Snoek L, van Kassel MN, Krommenhoek JF, Achten NB, Plötz FB, van Sorge NM, Brouwer MC, van de Beek D, Bijlsma MW; NOGBS study group.EClinicalMedicine. 2022 Jan 10;44:101270. doi: 10.1016/j.eclinm.2021.101270. eCollection 2022 Feb.

Nasal expression of SARS-CoV-2 entry receptors in newborns.

Heinonen S, Helve O, Andersson S, Janér C, Süvari L, Kaskinen A.Arch Dis Child Fetal Neonatal Ed. 2022 Jan;107(1):95-97. doi: 10.1136/archdischild-2020-321334. Epub 2021 May 14.

Maternal and Neonatal SARS-CoV-2 Immunoglobulin G Antibody Levels at Delivery After Receipt of the BNT162b2 Messenger RNA COVID-19 Vaccine During the Second Trimester of Pregnancy.

Kugelman N, Nahshon C, Shaked-Mishan P, Cohen N, Sher ML, Gruber M, Marom I, Zolotarevsky A, Lavie O, Damti A, Zilberlicht A, Bardicef M, Kedar R.JAMA Pediatr. 2022 Mar 1;176(3):290-295. doi: 10.1001/jamapediatrics.2021.5683.

Effect of prophylactic dextrose gel on the neonatal gut microbiome.

St Clair SL, Harding JE, O'Sullivan JM, Gamble GD, Alsweiler JM, Vatanen T; hPOD Study Group.Arch Dis Child Fetal Neonatal Ed. 2022 Sep;107(5):501-507. doi: 10.1136/archdischild-2021-322757. Epub 2021 Dec 2.

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