Pharmacology
📑 Journal Club Articles
Clonidine as Monotherapy for Neonatal Opioid Withdrawal Syndrome: A Randomized Trial.
Bada HS, Westgate PM, Sithisarn T, Yolton K, Charnigo R, Pourcyrous M, Tang F, Gibson J, Shearer-Miller J, Giannone P, Leggas M.Pediatrics. 2024 Oct 15:e2023065610. doi: 10.1542/peds.2023-065610. Online ahead of print.PMID: 39403061
EBNEO commentary: Patent ductus arteriosus (PDA)-To treat early or not with ibuprofen?
Javed R, Gowda H.Acta Paediatr. 2024 Apr 30. doi: 10.1111/apa.17259. Online ahead of print.PMID: 38687140 No abstract available.
Hydrocortisone in very preterm neonates for BPD prevention: meta-analysis and effect size modifiers.
De Luca D, Ferraioli S, Watterberg KL, Baud O, Gualano MR.Arch Dis Child Fetal Neonatal Ed. 2024 Jan 17:fetalneonatal-2023-326254. doi: 10.1136/archdischild-2023-326254. Online ahead of print.PMID: 38237961
Gentle SJ, Rysavy MA, Li L, Laughon MM, Patel RM, Jensen EA, Hintz S, Ambalavanan N, Carlo WA, Watterberg K; National Institute of Child Health and Human Development Neonatal Research Network.JAMA Netw Open. 2023 May 1;6(5):e2315315. doi: 10.1001/jamanetworkopen.2023.15315.PMID: 37256621 Free PMC article. Clinical Trial.
Miyake H, Chen Y, Hock A, Seo S, Koike Y, Pierro A.Pediatr Surg Int. 2018 May;34(5):491-497. doi: 10.1007/s00383-018-4242-4. Epub 2018 Mar 13.PMID: 29536176 Free PMC article. Review.
Ondansetron to reduce neonatal opioid withdrawal severity a randomized clinical trial.
Peltz G, Jansson LM, Adeniyi-Jones S, Cohane C, Drover D, Shafer S, Wang M, Wu M, Govindaswami B, Jegatheesan P, Argani C, Khan S, Kraft WK.J Perinatol. 2023 Mar;43(3):271-276. doi: 10.1038/s41372-022-01487-2. Epub 2022 Aug 27.PMID: 36030327 Free PMC article. Clinical Trial.
Overuse of Reflux Medications in Infants.
Wolf ER, Sabo RT, Lavallee M, French E, Schroeder AR, Huffstetler AN, Schefft M, Krist AH.Pediatrics. 2023 Mar 1;151(3):e2022058330. doi: 10.1542/peds.2022-058330.PMID: 36756736
Acetaminophen Use During Pregnancy and Children's Risk of Autism, ADHD, and Intellectual Disability.
Ahlqvist VH, Sjöqvist H, Dalman C, Karlsson H, Stephansson O, Johansson S, Magnusson C, Gardner RM, Lee BK.JAMA. 2024 Apr 9;331(14):1205-1214. doi: 10.1001/jama.2024.3172.PMID: 38592388
A phase I trial of caffeine to evaluate safety in infants with hypoxic-ischemic encephalopathy.
Jackson W, Gonzalez D, Greenberg RG, Lee YZ, Laughon MM.J Perinatol. 2024 Apr;44(4):508-512. doi: 10.1038/s41372-023-01752-y. Epub 2023 Aug 16.PMID: 37587184 Clinical Trial.
Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia.
Watterberg KL, Walsh MC, Li L, Chawla S, D'Angio CT, Goldberg RN, Hintz SR, Laughon MM, Yoder BA, Kennedy KA, McDavid GE, Backstrom-Lacy C, Das A, Crawford MM, Keszler M, Sokol GM, Poindexter BB, Ambalavanan N, Hibbs AM, Truog WE, Schmidt B, Wyckoff MH, Khan AM, Garg M, Chess PR, Reynolds AM, Moallem M, Bell EF, Meyer LR, Patel RM, Van Meurs KP, Cotten CM, McGowan EC, Hines AC, Merhar S, Peralta-Carcelen M, Wilson-Costello DE, Kilbride HW, DeMauro SB, Heyne RJ, Mosquera RA, Natarajan G, Purdy IB, Lowe JR, Maitre NL, Harmon HM, Hogden LA, Adams-Chapman I, Winter S, Malcolm WF, Higgins RD; Eunice Kennedy Shriver NICHD Neonatal Research Network.N Engl J Med. 2022 Mar 24;386(12):1121-1131. doi: 10.1056/NEJMoa2114897.PMID: 35320643 Free PMC article. Clinical Trial.
Use of Dexmedetomidine and Opioids in Hospitalized Preterm Infants.
Curtis S, Kilpatrick R, Billimoria ZC, Zimmerman K, Tolia V, Clark R, Greenberg RG, Puia-Dumitrescu M.JAMA Netw Open. 2023 Nov 1;6(11):e2341033. doi: 10.1001/jamanetworkopen.2023.41033.PMID: 37921767 Free PMC article.
Keij FM, Kornelisse RF, Hartwig NG, van der Sluijs-Bens J, van Beek RHT, van Driel A, van Rooij LGM, van Dalen-Vink I, Driessen GJA, Kenter S, von Lindern JS, Eijkemans M, Stam-Stigter GM, Qi H, van den Berg MM, Baartmans MGA, van der Meer-Kappelle LH, Meijssen CB, Norbruis OF, Heidema J, van Rossem MC, den Butter PCP, Allegaert K, Reiss IKM, Tramper-Stranders GA.Lancet Child Adolesc Health. 2022 Nov;6(11):799-809. doi: 10.1016/S2352-4642(22)00245-0. Epub 2022 Sep 9.
Oliphant EA, McKinlay CJ, McNamara D, Cavadino A, Alsweiler JM.Arch Dis Child Fetal Neonatal Ed. 2023 Mar;108(2):106-113. doi: 10.1136/archdischild-2022-324010. Epub 2022 Aug 29
Le J, Greenberg RG, Yoo Y, Clark RH, Benjamin DK Jr, Zimmerman KO, Cohen-Wolkowiez M, Wade KC; Best Pharmaceuticals for Children Act – Pediatric Trials Network Steering Committee.J Perinatol. 2022 Jul;42(7):959-964. doi: 10.1038/s41372-022-01344-2. Epub 2022 Feb 24.
Miller CJ, Prusakov P, Magers J, Speaks S, Sacic H, Escobar K, Abdel-Rasoul M, Nelin LD.J Perinatol. 2022 Dec;42(12):1644-1648. doi: 10.1038/s41372-022-01441-2. Epub 2022 Jun 25.
Sutter MB, Watson H, Yonke N, Weitzen S, Leeman L.BMC Pediatr. 2022 Jun 15;22(1):345. doi: 10.1186/s12887-022-03401-3.
Oral versus intravenous sildenafil for pulmonary hypertension in neonates: a randomized trial.
Chetan C, Suryawanshi P, Patnaik S, Soni NB, Rath C, Pareek P, Gupta B, Garegrat R, Verma A, Singh Y.BMC Pediatr. 2022 May 27;22(1):311. doi: 10.1186/s12887-022-03366-3.
Postnatal Corticosteroids to Prevent or Treat Chronic Lung Disease Following Preterm Birth
Authors: James J. Cummings, Arun K. Pramanik; Committee on Fetus and Newborn Journal: Pediatrics, 2022 DOI: 10.1542/peds.2022-057530
Li J, Zhang J, Hao Q, Chen H, Cheng X.Pediatr Pulmonol. 2022 Apr;57(4):1051-1063. doi: 10.1002/ppul.25837. Epub 2022 Jan 28.
Mitra S, Gardner CE, MacLellan A, Disher T, Styranko DM, Campbell-Yeo M, Kuhle S, Johnston BC, Dorling J.Cochrane Database Syst Rev. 2022 Apr 1;4(4):CD013846. doi: 10.1002/14651858.CD013846.pub2.
McDermott JH, Mahaveer A, James RA, Booth N, Turner M, Harvey KE, Miele G, Beaman GM, Stoddard DC, Tricker K, Corry RJ, Garlick J, Ainsworth S, Beevers T, Bruce IA, Body R, Ulph F, MacLeod R, Roberts PL, Wilson PM, Newman WG; PALOH Study Team.JAMA Pediatr. 2022 May 1;176(5):486-492. doi: 10.1001/jamapediatrics.2022.0187.
Dexmedetomidine affects cerebral activity in preterm infants.
Cortes-Ledesma C, Arruza L, Sainz-Villamayor A, Martínez-Orgado J.Arch Dis Child Fetal Neonatal Ed. 2023 May;108(3):316-318. doi: 10.1136/archdischild-2021-323411. Epub 2022 Mar 14.
Mank E, Sáenz de Pipaón M, Lapillonne A, Carnielli VP, Senterre T, Shamir R, van Toledo L, van Goudoever JB; FIT-04 Study Group.JAMA Pediatr. 2022 May 1;176(5):452-460. doi: 10.1001/jamapediatrics.2022.0020.
Vitamin K and the Newborn Infant.
Hand I, Noble L, Abrams SA.Pediatrics. 2022 Mar 1;149(3):e2021056036. doi: 10.1542/peds.2021-056036.PMID: 35190810
Oral versus intravenous paracetamol for patent ductus arteriosus closure in preterm infants.
Gover A, Levy PT, Rotschild A, Golzman M, Molad M, Lavie-Nevo K, Kessel I.Pediatr Res. 2022 Oct;92(4):1146-1152. doi: 10.1038/s41390-022-01944-w. Epub 2022 Jan 27.
O'Connor K, Hurst C, Llewellyn S, Davies M.Pediatr Pulmonol. 2022 Apr;57(4):1031-1041. doi: 10.1002/ppul.25821. Epub 2022 Jan 17.
Doyle LW, Cheong JL, Hay S, Manley BJ, Halliday HL.Cochrane Database Syst Rev. 2021 Oct 21;10(10):CD001146. doi: 10.1002/14651858.CD001146.pub6.PMID: 34674229